NATURAL MODULATION GUT MICROBIOTA IN PSIHOLOGIC STRESS: IMPACT OF DENIPLANT NUTRACEUTICALS

SSD JOURNAL 

3rd INTERNATIONAL CONFERENCE ON 

SOCIAL SCIENCES & HUMANITIES 

February 05-06, 2022 / Sanlıurfa,TURKEY 

THE PROCEEDINGS BOOK 

WEB: https:// www.ssdjournal.org 

E-MAIL: journalssd@gmail.com

277 

NATURAL MODULATION GUT MICROBIOTA IN PSIHOLOGIC STRESS: 

IMPACT OF DENIPLANT NUTRACEUTICALS 

Major Gheorghe Giurgiu 

Deniplant-Aide Sante Medical Center, Biomedicine 

ORCID: 0000-0002-5449-2712 

Prof. Dr. Manole Cojocaru

Titu Maiorescu University, Faculty of Medicine

ORCID: 0000-0002-6871-577X

ABSTRACT 

Background The gut microbiota may contribute to depressive symptoms. The gut microbiota 

may play a role in stress responding. The gut microbiota constitutes a dynamic microbial 

system constantly challenged by many biological variables, including environmental 

factors. Inflammation elevates risk for depression. Mounting evidence suggests that these 

anti-inflammatory effects are mediated by the microbiome. Stress and depression can increase 

gut barrier permeability. In turn, the gut bacteria release metabolites, toxins, and 

neurohormones. 

Obiectives To examine how diet and stress reciprocally interact with the gut microbiota and 

inflammation. To review different interventions that can modulate microbiota and could 

modulate the stress according to the underlying mechanisms whereby the gut-brain axis 

influences stress. 

Materials and methods Since the gut microbiota constitute a changeable and experience-

dependent ecosystem, they provide potential therapeutic targets that can be modulated as new 

interventions for dysbiosis-related disorders. 

Results A better understanding of the mechanism underlying stress modulation through the 

microbiota may open new avenues for the design of therapeutics that could boost the pursued 

clinical benefits. Diet functions as a major pathway from stress to gut dysbiosis. Healthier 

diets can reduce the risk of depression. Deniplant nutraceuticals improved sleep, autonomic 

balance, and bowel habits and reduced stress and cortisol levels 

Conclusion The influence of stress on gut microbiota and gut microbiota on stress modulation 

is clear for different stressors, but although the preclinical evidence is so extensive, the 

clinical evidence is more limited. Deniplant nutraceuticals may reduce inflammation and have 

positive effects on depression, anxiety, and stress. 

Keywords: diet, gut dysbiosis, gut-brain axis; stress, Deniplant nutraceuticals